CD44 anticorps

N° du produit ABIN298843

Cet anticorps Souris Monoclonal détecte spécifiquement CD44 dans FACS, WB, IHC, IHC (p), IP et IHC (fro). Il présente une réactivité envers Humain, Babouin et Green Monkey.

Aperçu rapide pour CD44 anticorps (ABIN298843)

Antigène: CD44

Reactivité: Humain, Babouin, Green Monkey

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD44 est non-conjugé

Application: Flow Cytometry (FACS), Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro))

Clone: 156-3C11

Détail du produit anti-CD44 anticorps

Specificité: Recognizes human CD44, a 90kD type I transmembrane protein which is otherwise known as HCAM or CD44s. Various isoforms of CD44 exist. The 90kD standard form, recognized by this, is expressed on leucocytes, erythrocytes, white matter of the brain and some epithelial cells of the breast and small intestine. Antibodies produced by clone 156-3C11 recognize epitope 3, which is a protease resistant epitope on the CD44 Molecule. CD44 is a receptor for hyaluronic acid (HA) and is involved in cell-cell interactions, cell adhesion and migration. CD44 also participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing. CD44 expression may be up-regulated upon some carcinomas, and it has been speculated that this may be related to metastatic potential.

Purification: Affinity purified

Immunogène: Stimulated human leucocytes.

Isotype: IgG2a

Information d'application

Indications d'application: Approved: Flo (1:50 - 1:100), IHC, IHC-Fr (1:100), IHC-P (1:100), IP, WB

Usage: Flow Cytometry: Use 10 μL of the suggested working dilution to label 1x10^6 cells in 100 μL. Method sheets are available on request. Western Blot: LS-C58044 detects a band of approximately 80kD in HeLa cell lysates. Immunohistology: This product requires

Commentaires:

Target Species of Antibody: Human

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: PBS,  pH 7.4, 0.09 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Short term: -20°C
Long term: -20°C.

Détails sur CD44

Antigène: CD44

Autre désignation: CD44

Sujet: Name/Gene ID: CD44

Synonyms: CD44, CDW44, CD44 antigen, Cell surface glycoprotein CD44, CSPG8, ECMR-III, Epican, HUTCH-I, LHR, MDU2, MC56, MIC4, Hermes antigen, Hyaluronate receptor, Phagocytic glycoprotein 1, PGP-1, PGP-I, Pgp1, Phagocytic glycoprotein I, MDU3, CD44R, HCELL, Heparan sulfate proteoglycan

ID gène: 960

Pathways: Glycosaminoglycan Metabolic Process, Autophagy, Negative Regulation of intrinsic apoptotic Signaling